Antiepileptic Drugs to Treat Psychiatric Disorders by Susan L. McElroy, Paul E. Keck Jr., Robert M. Post PDF

By Susan L. McElroy, Paul E. Keck Jr., Robert M. Post

ISBN-10: 0849382599

ISBN-13: 9780849382598

Several antiepileptic medicines (AEDs) now have regulatory symptoms for treating bipolar affliction. there's growing to be proof that AEDs regularly have numerous invaluable psychotropic results. Antiepileptic medications to regard Psychiatric issues is the 1st entire, clinically orientated reference at the use of AEDs to regard a number of psychiatric stipulations comparable to temper, psychotic, anxiousness, substance use, consuming, and character problems. Written by means of the major medical specialists, the booklet is equipped through psychiatric sickness for simpler info accumulating, allowing physicians to exploit the textual content as a standalone reference.

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IP dose-dependently ; cold and mechanical 29,30 allodynia and mechanical and thermal allodynia/hyperalgesia in mice. Dose-dependently ; mechanical hyperalgesia 10,16,25 (PO/IP); has no effect on tactile or cold allodynia (PO/IP); and has either no effect or ; mechanical allodynia in a dose-independent fashion in rats (PO/IP). PO lamotrigine dose-dependently ; mechanical 10 hyperalgesia in guinea pigs. IP levetiracetam has only a marginal effect on 12 mechanical hyperalgesia in rats. PO MHD and oxcarbazepine have no effect on 10 mechanical hyperalgesia, and PO oxcarbazepine has no effect on tactile allodynia in rats.

Medical therapy of epilepsy: when to initiate treatment and when to combine? J Neurol 2005; 252(2):125–130. 51. Beghi E, Gatti G, Tonini C, et al. BASE study group. Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial. Epilepsy Res 2003; 57(1):1–13. 3d] [29/4/08/11:27:19] [17–32] Antiepileptics in the Treatment of Epilepsy 31 52. Perucca E, Dulac O, Shorvon S, et al. Harnessing the clinical potential of antiepileptic drug therapy: dosage optimisation.

51. Beghi E, Gatti G, Tonini C, et al. BASE study group. Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial. Epilepsy Res 2003; 57(1):1–13. 3d] [29/4/08/11:27:19] [17–32] Antiepileptics in the Treatment of Epilepsy 31 52. Perucca E, Dulac O, Shorvon S, et al. Harnessing the clinical potential of antiepileptic drug therapy: dosage optimisation. CNS Drugs 2001; 15(8):609–621. 53. Perucca E.

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Antiepileptic Drugs to Treat Psychiatric Disorders by Susan L. McElroy, Paul E. Keck Jr., Robert M. Post


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