By Dennis F. Kohn, Sally K. Wixson, William J. White, G. John Benson
Anesthesia and Analgesia in Laboratory Animals focuses totally at the distinct anesthetic, analgesic, and postoperative care standards linked to experimental surgical procedure. backed through the yank university of Laboratory Animal drugs, this informative paintings presents the reader with brokers, tools, and strategies for anesthesia and analgesia that determine humane and profitable procedural results. Key positive factors* specializes in a wide selection of animal species utilized in learn* presents a entire assessment of the pharmacology of anesthetics and analgesics* comprises tracking of analgesia and anesthesia* Organizes themes by way of species for brokers and strategies of offering anesthesia, analgesia, and post-op care to animals* No different American textual content is dedicated completely to this subject
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Extra info for Anesthesia and Analgesia in Laboratory Animals (American College of Laboratory Animal Medicine Series)
Effects of althesin and urethan-chloralose on neurohumoral cardiovascular regulation. Am. J. Physiol. 256, R757-R765. Field, K. , and Lang, C. M. (1988). Hazards of urethane (ethyl carbamate): A review of the literature. Lab. Anim. 22, 255-262. Field, K. , White, W. , and Lang, C. M. (1993). Anaesthetic effects of chloral hydrate, pentobarbitone and urethane in adult male rats. Lab. Anim. 27, 258-269. File, S. , and Simmonds, M. A. (1988). Myoclonic seizures in the mouse induced by alphaxalone and related steroid anaesthetics.
Aramayona, J. , and Bonati, M. (1992). Monitoring of blood gas parameters and acid-base balance of pregnant and non-pregnant rabbits (Oryctolagus cuniculus) in routine experimental conditions. Lab. Anim. 26, 73-79. Batjer, H. H. (1993). Cerebral protective effects of etomidate: Experimental and clinical aspects. Cerebrovasc. Brain Metab. Rev. 5, 17-32. Bellman, M. , and Pleuvry, B. J. (1981). Comparison of the respiratory effects of IC135 868 and thiopentone in the rabbit. Br. J. Anaesth. 53,425-429.
Three %agonists are commonly used clinically: xylazine, detomidine, and medetomidine. known to be important in the regulation of vigilance (Stenberg, 1989; Virtanen, 1989). Evidence also shows %-mediated antinociceptive effects at the level of the spinal cord (Takano and Yaksh, 1992; Virtanen, 1986). %-Agonism in the periphery causes vasoconstriction, decreased insulin release, diuresis, decreased gastrointestinal motility, and thrombasthenia (Haskins, 1992). Other ct2-agonists such as clonidine are used clinically for the treatment of hypertension, migraine prophylaxis, and relief of heroin withdrawal symptoms (Scheinin and MacDonald, 1989).
Anesthesia and Analgesia in Laboratory Animals (American College of Laboratory Animal Medicine Series) by Dennis F. Kohn, Sally K. Wixson, William J. White, G. John Benson